There is a new version of one of the oldest, if not the oldest, a frontend for MAME - Mame Classic. MC is terribly annoying to set up, does not like the x64, but the Conservatives have a full range of facilities which allows you to bypass all the arcade machines, which are not included in the canon of author Richard A. Insalaco (NeoGeo ranging from nasty :) :).

Pantheon is Windows desktop application that allows you to play games for various gaming consoles and home computers from the past. The games are not the part of the application, instead they will be downloaded (with the game manual - if available). Pantheon is still in development. Current version includes emulators of Acorn Atom, Acorn BBC Micro, Acorn Electron, Atari 2600, Atari 5200, Atari 7800, Atari 8-bit computers, Atari Lynx, ColecoVision, Magnavox Odyssey2, MSX computers, Sega Master System and Sega Game Gear. You may experience occasional artifacts or crashes during the gameplay and save files for certain device may not be available in the next releases, if the emulator will be changed. Currently It support (Acorn Atom (68 games), Acorn BBC Micro (398 games),  Acorn Electron (278 games),  Atari 2600 (594 games),  Atari 5200 (94 Read more

QmameCab is a frontend written in QT supports emulators MAME / MESS. The reigning crush stands out among the overlay module supports quite clever MESS'a has, and how the possibility of transferring commands for the filter HLSL, displays everything possible to show when it comes to information about supported hardware - including information downloaded from Maws . In addition, the next version will support also QMC2 UME (Universal Machine Emulator) , which is an attempt to connect with one of MAME and MESS multiemulatorów. If we add to this multitude Read more

MESSUI is an integrated frontend of MESS, which itself emulates 100 of computers & consoles. MESSUI is similar in appearance to MAMEUI. Each emulation instance is accompanied by a windows-style menubar. This menubar is known as 'NEWUI'.